The brainstem plays a crucial role in sleep-wake regulation.However, the ensemble dynamics underlying sleep regulation remain poorly understood.Here, we show slow, state-predictive brainstem ensemble dynamics and state-dependent interactions between the brainstem and the hippocampus in mice.On a timescale of seconds to minutes, brainstem population
Qualitative research in the health sciences has had to overcome many prejudices and a number of misunderstandings, but today qualitative research is as acceptable as quantitative research designs and is widely funded and published.Writing the proposal of a qualitative study, however, can be a challenging feat, due to the emergent nature of the qual
While 60 years of successful application of holography is celebrated in this special issue, efficient representation and compression of holographic data has received relatively little attention in research.Notwithstanding this observation, and particularly due to the digitization that is also penetrating the holographic domain, interest is growing
Registration of histological serial sections is a challenging task.Serial sections exhibit distortions and damage from sectioning.Missing information on how the tissue looked before cutting makes a realistic validation of Breast Milk Storage Containers 2D registrations extremely difficult.This work proposes methods for ground-truth-based evaluation
The 18th century was a time of considerable challenges for monastic life, both in general and for specific congregations.Let us recall such events as the abolition of Jesuit reductions in Paraguay, expelling Jesuits from Portugal and Spain, the dissolution of the Society of Jesus, the closure of hundreds of monastic houses as part of Josephine refo